Parkinson’s is found all over the world. Exact global figures are not always available, though it is estimated that four million people worldwide have the condition. Parkinson’s disease belongs to a group of conditions called movement disorders. Parkinson’s disease afflicts 1 to 1 1/2 million people in the United States. The disorder occurs in all races but is somewhat more prevalent among Caucasians. People with the disease may have trouble walking, talking or doing simple tasks. Dysfunctional antioxidative mechanisms are associated with older age as well, suggesting that the acceleration of age-related changes in dopamine production may be a factor. Parkinson’s disease patients have at least one relative with parkinsonian symptoms, suggesting that a genetic factor may be involved. There is no cure for Parkinson’s at present, drugs are used to try to control symptoms of Parkinson’s. The most widely used form of treatment is L-dopa in various forms. L-dopa is transformed into dopamine in the dopaminergic neurons by L-aromatic amino acid decarboxylase (often known by its former name dopa-decarboxylase). The most widely practiced treatment for the speech disorders associated with Parkinson’s disease is Lee Silverman Voice Treatment (LSVT). LSVT focuses on increasing vocal loudness. Regular physical exercise and/or therapy can be beneficial to the patient for maintaining and improving mobility, flexibility, balance and a range of motion. Nutrients have been used in clinical studies and are widely used by people with Parkinson’s disease in order to partially treat PD or slow down its deterioration.
Causes of Parkinsons Disease
Common Causes and Risk factors of Parkinsons Disease
Carbon monoxide poisoning.
Signs and Symptoms of Parkinsons Disease
Common Sign and Symptoms of Parkinsons Disease
Depression and other emotional changes.
Difficulty in swallowing.
Chewing, and speaking.
Trembling of hands, arms, legs, jaw and face.
Treatment of Parkinsons Disease
Common Treatment of Parkinsons Disease
Successful treatment of Parkinson’s disease involves much more than just the use of drugs. Levodopa and carbidopa combined (Sinemet) is the mainstay of Parkinson’s therapy.
Tolcapone inhibits the COMT enzyme, thereby prolonging the effects of L-dopa, and so has been used to complement L-dopa.
The most widely practiced treatment for the speech disorders associated with Parkinson’s disease is Lee Silverman Voice Treatment (LSVT).
Nutrients have been used in clinical studies and are widely used by people with Parkinson’s disease in order to partially treat PD or slow down its deterioration.
Catechol O-methyl transferase (COMT) inhibitors act by inhibiting catabolism of dopamine, thereby extending L-dopa’s peripheral half-life.
Surgical treatment for PD is generally considered for patients who respond to medications.
Azilect was approved for use as an initial single drug therapy in early Parkinson’s disease. Azilect (rasagiline), a new molecular entity, for the treatment of Parkinson’s disease.
Physical therapy can help strengthen and tone underused muscles, and give rigid muscles a better range of motion.