The life expectation for people with cystic fibrosis has been steadily increasing over the past 40 years. Some people with CF have serious lung and digestive problems. Other people have more mild disease that doesn’t show up until they are adolescents or young adults. CF is caused by a mutation in a gene called the cystic fibrosis transmembrane conductance regulator (CFTR). Respiratory failure is the most dangerous consequence of cystic fibrosis. Also, the secretions block pancreatic enzymes that help digest fats and proteins, and they prevent your body from absorbing key vitamins. Treatments for cystic fibrosis are aimed at relieving symptoms and complications.
Causes of Cystic Fibrosis
The common Causes of Cystic Fibrosis :
Cystic fibrosis affects the mucus and sweat glands of the body and is caused by a defective gene .
Other bacteria may be involved.
Radiation, eg after radiotherapy to other organs in the pelvis.
The main cause of cystitis fibrosis (and other urinary tract infections) is bacteria known as coliform bacteria, which are a common occupant of the bowel.
Symptoms of Cystic Fibrosis
Some Symptoms of Cystic Fibrosis :
Weight loss, or failure to gain weight normally in childhood .
Coughing or wheezing.
Infants may have salty-tasting skin.
Recurrent respiratory infections, such as pneumonia or sinusitis.
Stools that are pale or clay colored , foul smelling, or that float.
Delayed growth .
Treatment of Cystic Fibrosis
Antibiotics for respiratory infections.
Vitamin supplements, especially vitamins A, D, E, and K.
DNAse enzyme replacement therapy. The medication dornase (Pulmozyme) contains an enzyme that thins the mucus and makes it easier to cough up.
Postural drainage and chest percussion .
Lung transplant may be considered in some cases.
Pancreatic enzymes to replace those that are missing.
Research has shown that the pain reliever ibuprofen may slow lung deterioration in some children with cystic fibrosis. The results were most dramatic in children ages 5 to 13